The Sec domain protein Scfd1 facilitates trafficking of ECM components during chondrogenesis.

Abstract

Chondrogenesis in the developing skeleton requires transformation of chondrocytes from a simple mesenchymal condensation to cells with a highly enriched extracellular matrix (ECM). This transition is in part accomplished by alterations in the chondrocyte protein transport machinery to cope with both the increased amount and large size of ECM components. In… (More)
DOI: 10.1016/j.ydbio.2016.11.010

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