The Search for Insulin

  title={The Search for Insulin},
  author={I. P. C. Murray},
  journal={Scottish Medical Journal},
  pages={286 - 293}
  • I. Murray
  • Published 1 August 1969
  • Medicine
  • Scottish Medical Journal
From pancreatic extracts to artificial pancreas: History, science and controversies about the discovery of the pancreatic antidiabetic hormone. VII: Early clinical use of pancreatic extracts (1921-1923)
The Nobel Award of Physiology and Medicine was jointly granted to Frederick Grant Banting and John James Richard Macleod, “for the discovery of insulin”, one year before.
Pancreatic Extracts for the Treatment of Diabetes (1889-1914): Acomatol.
The organotherapy of diabetes was a paradigm for the integration of basic and applied knowledge about hormone action and development of endocrine pharmacology and demonstrated that diabetes is a pancreatic disease.
Nicolae Constantin Paulescu: the first explicit description of the internal secretion of the pancreas.
Nicolae Constantin Paulescu thought that a new hormone - Pancreine, that he discovered is the key element in the treatment of diabetes, but his outstanding research was unfairly neglected.
Diabetes mellitus: a complete ancient and modern historical perspective
This review aims to explore the timeline of diabetes journey, and correct the inconsistencies in the historical perspectives of diabetes with intent to project the future.
Agmatine: clinical applications after 100 years in translation.
This timely review, a concerted effort by 16 independent research groups, draws attention to the substantial preclinical and initial clinical evidence, and highlights challenges and opportunities, for the use of agmatine in treating a spectrum of complex diseases with unmet therapeutic needs.
[The discovery of insulin: continued controversies after ninety years].
La introduccion de insulina en el tratamiento de la diabetes mellitus represento un impacto clinicosocial, similar al de la antibioterapia. Hacia mediados del siglo XX, los pacientes con instauracion
[The discovery of insulin: continued controversies after ninety years].
The introduction of insulin into the treatment of diabetes mellitus had a clinical and social impact similar to that of the introduction of antibiotic therapy. By the middle of the 20th century,
A tale of two hormones
A little more than a century ago, an arc of research began that culminated in the identification of insulin by four scientists working in Toronto, which changed the treatment of diabetes forever by providing a hormonal treatment from the pancreas that could rapidly restore bedridden, cachectic and moribund children and young adults to healthy lives.
From pancreatic extracts to artificial pancreas: History, science and controversies about the discovery of the pancreatic antidiabetic hormone VIII: Step by step towards the artificial pancreas
The word eugenics was coined in 1883 by the English scientist Francis Galton, a cousin of Charles Darwin, to promote the ideal of perfecting the human race by encouraging the procreation of the social Darwinian fi t and discouraging that of the unfi t.


Memories of James Bertram Collip.
[Internal secretion].
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Recherche sur Ie role du pancreas dans l'assiucitation nutritive
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Internal Secretion and the Ductless Glands
PROF. SWALE VINCENT is well known as an investigator who has devoted much attention to one of the most interesting chapters of physiology, namely, that which deals with the group of organs, formerly
Trypsinogen und Enterokinase beim menschlichen Neugebornen und Embryo
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