The Sanger Mouse Genetics Programme: high throughput characterisation of knockout mice

@article{Gerdin2010TheSM,
  title={The Sanger Mouse Genetics Programme: high throughput characterisation of knockout mice},
  author={Ak Gerdin},
  journal={Acta Ophthalmologica},
  year={2010},
  volume={88}
}
  • Ak Gerdin
  • Published 2010
  • Biology
  • Acta Ophthalmologica
  • Purpose The Sanger Mouse Genetics Programme (MGP) aims to make a significant impact on our understanding of the function of genes and their role in disease by generating, characterising and archiving in the order of 200 lines of knockout mice per year, including 40 lines as part of the EUMODIC consortium. The phenotyping screens employed include a wide range of assays relevant to key disease areas including diabetes, obesity, hearing and vision disorders, immune disorders, pain and motor… CONTINUE READING
    22 Citations
    Identification and Validation of DLG2 as a Novel Tumor Suppressor in Osteosarcoma
    • PDF
    Molecular genetic investigation of medullary thyroid cancer
    • PDF
    Genome-wide association study reveals genetic loci and candidate genes for average daily gain in Duroc pigs
    • 7
    • PDF
    Mammalian phospholipase D: Function, and therapeutics.
    • 7
    The phospholipase D superfamily as therapeutic targets.
    • M. Frohman
    • Biology, Medicine
    • Trends in pharmacological sciences
    • 2015
    • 113
    Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.
    • 32
    • PDF