The Sanger Mouse Genetics Programme: high throughput characterisation of knockout mice

  title={The Sanger Mouse Genetics Programme: high throughput characterisation of knockout mice},
  author={Ak Gerdin},
  journal={Acta Ophthalmologica},
  • A. Gerdin
  • Published 1 September 2010
  • Biology
  • Acta Ophthalmologica
Purpose The Sanger Mouse Genetics Programme (MGP) aims to make a significant impact on our understanding of the function of genes and their role in disease by generating, characterising and archiving in the order of 200 lines of knockout mice per year, including 40 lines as part of the EUMODIC consortium. The phenotyping screens employed include a wide range of assays relevant to key disease areas including diabetes, obesity, hearing and vision disorders, immune disorders, pain and motor… Expand
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