The Salvador/Warts/Hippo pathway controls regenerative tissue growth in Drosophila melanogaster.

@article{Grusche2011TheSP,
  title={The Salvador/Warts/Hippo pathway controls regenerative tissue growth in Drosophila melanogaster.},
  author={Felix A. Grusche and Joffrey L. Degoutin and Helena E Richardson and Kieran F. Harvey},
  journal={Developmental biology},
  year={2011},
  volume={350 2},
  pages={255-66}
}
During tissue regeneration, cell proliferation replaces missing structures to restore organ function. Regenerative potential differs greatly between organs and organisms; for example some amphibians can regrow entire limbs whereas mammals cannot. The process of regeneration relies on several signaling pathways that control developmental tissue growth, and implies the existence of organ size-control checkpoints that regulate both developmental, and regenerative, growth. Here we explore the role… CONTINUE READING