The Safety and Efficacy of Low‐Dose Naltrexone in the Management of Chronic Pain and Inflammation in Multiple Sclerosis, Fibromyalgia, Crohn's Disease, and Other Chronic Pain Disorders

@article{Patten2018TheSA,
  title={The Safety and Efficacy of Low‐Dose Naltrexone in the Management of Chronic Pain and Inflammation in Multiple Sclerosis, Fibromyalgia, Crohn's Disease, and Other Chronic Pain Disorders},
  author={Denise K. Patten and Bob G. Schultz and Daniel J Berlau},
  journal={Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy},
  year={2018},
  volume={38}
}
  • Denise K. Patten, Bob G. Schultz, Daniel J Berlau
  • Published 2018
  • Medicine
  • Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
  • Chronic inflammatory diseases are complex to treat and have an impact on a large number of patients. Due to the difficulty of treating these diseases and the great impact on quality of life, patients often seek off‐label, complimentary, or alternative medicines to gain relief from symptoms. Low‐dose naltrexone has been used off‐label for treatment of pain and inflammation in multiple sclerosis, Crohn's disease, fibromyalgia, and other diseases. Naltrexone is a mu‐opioid receptor antagonist… CONTINUE READING
    24 Citations

    Paper Mentions

    INTERVENTIONAL CLINICAL TRIAL
    Interstitial cystitis/painful bladder syndrome (IC/PBS) is a debilitating condition with symptoms of urinary urgency, frequency, nocturia (waking up at night to void), and pain… Expand
    ConditionsBladder Pain Syndrome, Interstitial Cystitis, Low-dose Naltrexone, (+3 more)
    InterventionDrug
    Low-Dose Naltrexone (LDN)—Review of Therapeutic Utilization
    • 16
    • PDF
    The uses of naltrexone in dermatologic conditions.
    • 7
    Opioid‐induced hypogonadism: Pathophysiology, clinical and therapeutics review
    • 3

    References

    SHOWING 1-10 OF 61 REFERENCES
    The use of low-dose naltrexone (LDN) as a novel anti-inflammatory treatment for chronic pain
    • 92
    • PDF
    Low Dose Naltrexone in the Treatment of Fibromyalgia.
    • 9
    Therapy with the Opioid Antagonist Naltrexone Promotes Mucosal Healing in Active Crohn’s Disease: A Randomized Placebo-Controlled Trial
    • 83
    • PDF
    Fibromyalgia symptoms are reduced by low-dose naltrexone: a pilot study.
    • 125
    • PDF
    Low dose naltrexone for induction of remission in Crohn's disease.
    • 21
    • PDF