The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase.

@article{Roberts1994TheSC,
  title={The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase.},
  author={B Tibor Roberts and K A Farr and Martin A. Hoyt},
  journal={Molecular and cellular biology},
  year={1994},
  volume={14 12},
  pages={8282-91}
}
Normal cell multiplication requires that the events of mitosis occur in a carefully ordered fashion. Cells employ checkpoints to prevent cycle progression until some prerequisite step has been completed. To explore the mechanisms of checkpoint enforcement, we previously screened for mutants of Saccharomyces cerevisiae which are unable to recover from a transient treatment with a benzimidazole-related microtubule inhibitor because they fail to inhibit subsequent cell cycle steps. Two of the… CONTINUE READING
Highly Influential
This paper has highly influenced a number of papers. REVIEW HIGHLY INFLUENTIAL CITATIONS