The Saccharomyces cerevisiae SSD1 gene is involved in the tolerance to high concentration of Ca2+ with the participation of HST1/NRC1/BFR1.

@article{Tsuchiya1996TheSC,
  title={The Saccharomyces cerevisiae SSD1 gene is involved in the tolerance to high concentration of Ca2+ with the participation of HST1/NRC1/BFR1.},
  author={Eiko Tsuchiya and Goro Matsuzaki and Kozo Kurano and Takeshi Fukuchi and A Tsukao and Tokichi Miyakawa},
  journal={Gene},
  year={1996},
  volume={176 1-2},
  pages={35-8}
}
The SSD1 gene of Saccharomyces (S.) cerevisiae is a polymorphic gene involved in many aspects of the yeast cell growth (Sutton et al., 1991). We found that ssd1 null mutant shows increased sensitivities of growth to trifluoperazine (TFP) and high concentration of Ca2+. A high-copy suppressor gene, HST1, for the TFP and Ca2+ sensitivities of ssd1 null mutant was cloned and sequenced. The HST1 gene encodes a polypeptide of 915 amino acids, and is identical to the NRC1/BRF1 gene in databases. The… CONTINUE READING

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