The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae.

@article{Blumer1988TheSG,
  title={The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae.},
  author={Kendall J Blumer and J E Reneke and J. Thorner},
  journal={The Journal of biological chemistry},
  year={1988},
  volume={263 22},
  pages={10836-42}
}
The STE2 gene of Saccharomyces cerevisiae encodes a 431-residue protein containing seven hydrophobic segments that is thought to be an essential component of the cell-surface receptor for alpha-factor in MATa haploids. Methods were devised to prepare membrane fractions from MATa cells that retained high levels of alpha-factor binding activity, consistent with the view that the alpha-factor receptor resides in the plasma membrane. To demonstrate that the membrane constituent responsible for… CONTINUE READING
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