The SR protein family of splicing factors: master regulators of gene expression.

@article{Long2009TheSP,
  title={The SR protein family of splicing factors: master regulators of gene expression.},
  author={Jennifer C Long and Javier F C{\'a}ceres},
  journal={The Biochemical journal},
  year={2009},
  volume={417 1},
  pages={15-27}
}
The SR protein family comprises a number of phylogenetically conserved and structurally related proteins with a characteristic domain rich in arginine and serine residues, known as the RS domain. They play significant roles in constitutive pre-mRNA splicing and are also important regulators of alternative splicing. In addition they participate in post-splicing activities, such as mRNA nuclear export, nonsense-mediated mRNA decay and mRNA translation. These wide-ranging roles of SR proteins… CONTINUE READING
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