The SNO-proteome: causation and classifications.

  title={The SNO-proteome: causation and classifications.},
  author={Divya Seth and Jonathan S. Stamler},
  journal={Current opinion in chemical biology},
  volume={15 1},
Cell signaling is a complex and highly regulated process. Post-translational modifications of proteins serve to sense and transduce cellular signals in a precisely coordinated manner. It is increasingly recognized that protein S-nitrosylation, the addition of a nitric oxide group to cysteine thiols, serves an important role in a wide range of signaling pathways. In spite of the large number of SNO-proteins now identified (∼1000), the observed specificity of S-nitrosylation in terms of target… CONTINUE READING

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