The SLP-76 Src homology 2 domain is required for T cell development and activation.

Abstract

The adapter protein Src homology 2 (SH2) domain-containing leukocyte protein of 76 kDa (SLP-76) is critical for multiple aspects of T cell development and function. Through its protein-binding domains, SLP-76 serves as a platform for the assembly of multiple enzymes and adapter proteins that function together to activate second messengers required for TCR… (More)
DOI: 10.4049/jimmunol.0903379

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@article{Burns2011TheSS, title={The SLP-76 Src homology 2 domain is required for T cell development and activation.}, author={Jeremy C Burns and Evann Corbo and Janine Degen and Mercy Gohil and Christine Anterasian and Burkart Schraven and Gary A Koretzky and Stefanie Kliche and Martha S Jordan}, journal={Journal of immunology}, year={2011}, volume={187 9}, pages={4459-66} }