The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport.

@article{Thwaites2011TheSF,
  title={The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport.},
  author={David T. Thwaites and Catr{\`i}ona Anderson},
  journal={British journal of pharmacology},
  year={2011},
  volume={164 7},
  pages={1802-16}
}
Members of the solute carrier (SLC) 36 family are involved in transmembrane movement of amino acids and derivatives. SLC36 consists of four members. SLC36A1 and SLC36A2 both function as H(+) -coupled amino acid symporters. SLC36A1 is expressed at the luminal surface of the small intestine but is also commonly found in lysosomes in many cell types (including neurones), suggesting that it is a multipurpose carrier with distinct roles in different cells including absorption in the small intestine… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 32 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 121 references

H+-coupled PAT1 (SLC36A1) and Na+ and Cl- dependent TauT (SLC6A6)

  • CMH Anderson, M Jevons, M Thangaraju, N Edwards, NJ Conlon, S Woods
  • J Physiol
  • 2010
Highly Influential
8 Excerpts

Similar Papers

Loading similar papers…