The SLC2 family of facilitated hexose and polyol transporters

@article{Uldry2003TheSF,
  title={The SLC2 family of facilitated hexose and polyol transporters},
  author={M. Uldry and B. Thorens},
  journal={Pfl{\"u}gers Archiv},
  year={2003},
  volume={447},
  pages={480-489}
}
  • M. Uldry, B. Thorens
  • Published 2003
  • Chemistry
  • Pflügers Archiv
  • The SLC2 family of glucose and polyol transporters comprises 13 members, the glucose transporters (GLUT) 1–12 and the H+-myo-inositol cotransporter (HMIT). These proteins all contain 12 transmembrane domains with both the amino and carboxy-terminal ends located on the cytoplasmic side of the plasma membrane and a N-linked oligosaccharide side-chain located either on the first or fifth extracellular loop. Based on sequence comparison, the GLUT isoforms can be grouped into three classes: class I… CONTINUE READING
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