The SH2-containing 5'-inositol phosphatase (SHIP) is tyrosine phosphorylated after Fc gamma receptor clustering in monocytes.

@article{Maresco1999TheS5,
  title={The SH2-containing 5'-inositol phosphatase (SHIP) is tyrosine phosphorylated after Fc gamma receptor clustering in monocytes.},
  author={Diane L. Maresco and Jeanne M. Osborne and D. Paul Cooney and K Mark Coggeshall and Clark Anderson},
  journal={Journal of immunology},
  year={1999},
  volume={162 11},
  pages={6458-65}
}
Current models of Fc gamma R signal transduction in monocytes describe a molecular cascade that begins upon clustering of Fc gamma R with the phosphorylation of critical tyrosine residues in the cytoplasmic domains of Fc gamma RIIa or the gamma-chain subunit of Fc gamma RI and Fc gamma RIIIa. The cascade engages several other tyrosine-phosphorylated… CONTINUE READING