The S. mansoni glycoprotein ω-1 induces Foxp3 expression in NOD mouse CD4⁺ T cells.

@article{Zaccone2011TheSM,
  title={The S. mansoni glycoprotein ω-1 induces Foxp3 expression in NOD mouse CD4⁺ T cells.},
  author={Paola Zaccone and Oliver Burton and Sarah E Gibbs and Nigel Miller and Frances M. Jones and Gabriele Schramm and H. P. A. Haas and Michael J. Doenhoff and David W. Dunne and Anne Cooke},
  journal={European journal of immunology},
  year={2011},
  volume={41 9},
  pages={2709-18}
}
Immunization with Schistosoma mansoni soluble antigen preparations protects non-obese diabetic (NOD) mice against the development of type 1 diabetes. These preparations have long been known to induce Th2 responses in vitro and in vivo. Recently, two separate groups have reported that ω-1, a well-characterized glycoprotein in S. mansoni soluble egg antigens (SEA), which with IL-4 inducing principle of S. mansoni eggs (IPSE/α-1) is one of the two major glycoproteins secreted by live eggs, is a… CONTINUE READING
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