The RuvABC resolvasome.

  title={The RuvABC resolvasome.},
  author={Mark J. Dickman and Stuart M. Ingleston and Svetlana E. Sedelnikova and John B Rafferty and R. G. Lloyd and Jane A. Grasby and David P Hornby},
  journal={European journal of biochemistry},
  volume={269 22},
The RuvABC resolvasome of Escherichia coli catalyses the resolution of Holliday junctions that arise during genetic recombination and DNA repair. This process involves two key steps: branch migration, catalysed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein, and resolution, which is catalysed by the RuvC endonuclease. We have quantified the interaction of the RuvA protein with synthetic Holliday junctions and have shown that the binding of… 

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