The Ruminococci: key symbionts of the gut ecosystem

@article{Reau2018TheRK,
  title={The Ruminococci: key symbionts of the gut ecosystem},
  author={Alex La Reau and G. Suen},
  journal={Journal of Microbiology},
  year={2018},
  volume={56},
  pages={199-208}
}
Mammalian gut microbial communities form intricate mutualisms with their hosts, which have profound implications on overall health. One group of important gut microbial mutualists are bacteria in the genus Ruminococcus, which serve to degrade and convert complex polysaccharides into a variety of nutrients for their hosts. Isolated decades ago from the bovine rumen, ruminococci have since been cultured from other ruminant and non-ruminant sources, and next-generation sequencing has further shown… Expand

Paper Mentions

Profiling of Protein Degraders in Cultures of Human Gut Microbiota
TLDR
Light is shed on the multitude of bacterial taxa putatively participating in protein catabolism in the colon, due to both the production of toxic metabolites and the blooming of opportunistic pathogens and pro-inflammatory bacteria. Expand
Multi-omics Approaches To Decipher the Impact of Diet and Host Physiology on the Mammalian Gut Microbiome
TLDR
The analyses performed in this study support the notion that the metabolic features of the mammalian gut microbiota have adapted to maximize energy extraction from the host’s diet. Expand
Characterization of a novel Pantoea symbiont allows inference of a pattern of convergent genome reduction in bacteria associated with Pentatomidae.
TLDR
A novel Pantoea species was characterized from the gut of pentatomid Acrosternum arabicum, and shown to be highly abundant in a specific portion of the gut and necessary for the host development, highlighting a convergent pattern of genome reduction in symbionts ofpentatomids. Expand
Puffer Fish Gut Microbiota Studies Revealed Unique Bacterial Co-Occurrence Patterns and New Insights on Tetrodotoxin Producers
TLDR
This is the first study to profile the gut microbiota in toxic and non-toxic puffer fish species by 16S rRNA amplicon metagenomic approach, defining significant microbial co-occurrence patterns in their gut environment and supported the proposed biosynthesis of TTX inside the hosts by their gut bacterial symbionts using arginine as a precursor. Expand
Gut microbiota are associated with sex and age of host: Evidence from semi‐provisioned rhesus macaques in southwest Guangxi, China
TLDR
Variation in the gut microbiota of different sex and age classes of rhesus macaques may be linked to age‐ and sex‐specific differences in nutrient requirements and hormone levels, highlighting the importance of host age and sex on the structure and function of the Gut microbiota and the need to consider physiological traits when conducting studies on the gut microbiome. Expand
Acceptive Immunity: The Role of Fucosylated Glycans in Human Host–Microbiome Interactions
TLDR
This review discusses the establishment of homeostatic relationships during immune system development and intestinal bacterial colonization through the interaction of milk glycans, mucins, and secretory immunoglobulins and the role of fucose and fucosylated glycans in the mechanism of interactions between host epithelial and immune cells. Expand
Transformation of bacterial community structure in rumen liquid anaerobic digestion of rice straw.
TLDR
The high-throughput sequencing results showed that structure of rumen bacterial community significantly changed in anaerobic digestion, and the function prediction found that rumen bacteria mainly functioned in carbohydrate transport and metabolism, which might contain a large number of lignocellulose degrading enzyme genes. Expand
Rumen Microbiome Composition Is Altered in Sheep Divergent in Feed Efficiency
TLDR
Evidence is provided that feed efficiency in sheep is likely influenced by compositional changes to the archaeal community, and abundance changes of specific bacteria, rather than major overall shifts within the rumen microbiome. Expand
Developmental symbiosis facilitates the multiple origins of herbivory
  • S. Gilbert
  • Biology, Medicine
  • Evolution & development
  • 2019
TLDR
It is posited that the behavioral and morphological manifestations of herbivorous phenotypes must be preceded by the successful establishment of a community of symbiotic microbes that can digest cell walls and detoxify plant poisons. Expand
Flexibility and resilience of great tit (Parus major) gut microbiomes to changing diets
TLDR
The gut microbial response and partial resilience to dietary changes support that gut bacterial communities of P. major play a role in accommodating dietary changes experienced by wild avian hosts, and imply that interpretations of wild bird gut microbiome analyses from single-time point sampling, especially for omnivorous species or species with seasonally changing diets, should be done with caution. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 108 REFERENCES
Sequence-based analysis of the genus Ruminococcus resolves its phylogeny and reveals strong host association
TLDR
Evidence that ruminococci are predominantly associated with herbivores and omnivores is presented, and the hypothesis that very few ruminitisci are found consistently in non-host-associated environments is supported, to help resolve the phylogeny of this important genus. Expand
Erratum: Rumen microbial community composition varies with diet and host, but a core microbiome is found across a wide geographical range
TLDR
There were few strong co-occurrence patterns between microbes, suggesting that major metabolic interactions are non-selective rather than specific, and could make it possible to mitigate methane emissions by developing strategies that target the few dominant methanogens. Expand
Ruminococcus bromii is a keystone species for the degradation of resistant starch in the human colon
TLDR
It is argued strongly that R. bromii has a pivotal role in fermentation of RS3 in the human large intestine, and that variation in the occurrence of this species and its close relatives may be a primary cause of variable energy recovery from this important component of the diet. Expand
Ruminococcus champanellensis sp. nov., a cellulose-degrading bacterium from human gut microbiota.
TLDR
On the basis of phylogenetic analysis, and morphological and physiological data, strain 18P13(T) can be differentiated from other members of the genus Ruminococcus with validly published names. Expand
Utilisation of Mucin Glycans by the Human Gut Symbiont Ruminococcus gnavus Is Strain-Dependent
TLDR
It is shown that although both strains could assimilate mucin monosaccharides, only R. gnavus ATCC 29149 was able to grow on mucin as a sole carbon source, and a novel pathway by which R.gnavusATCC29149 utilises sialic acid from sialylated substrates is uncovered, advancing understanding of the role of gut commensals in health and disease. Expand
Ruminococcal cellulosome systems from rumen to human.
TLDR
A cellulolytic fiber-degrading bacterium, Ruminococcus champanellensis, was isolated from human faecal samples, and its genome was recently sequenced, revealing two large tandem scaffoldin-coding genes that form part of a gene cluster. Expand
Ruminococcus faecis sp. nov., isolated from human faeces
TLDR
It is proposed that this novel strain isolated from human faeces be assigned to the genus Ruminococcus and be named Ruminitis faecis sp. Expand
Rumen Cellulosomics: Divergent Fiber-Degrading Strategies Revealed by Comparative Genome-Wide Analysis of Six Ruminococcal Strains
TLDR
This work provides blueprints of the divergent cellulolytic systems in these two prominent fibrolytic rumen bacterial species, each of which reflects a distinct mechanistic model for efficient degradation of cellulosic biomass. Expand
Unique aspects of fiber degradation by the ruminal ethanologen Ruminococcus albus 7 revealed by physiological and transcriptomic analysis
TLDR
Comparative genomics, fermentation analyses, and transcriptomics are used to further clarify the cellulolytic and fermentative potential of R. albus 7 and contribute to a revised model of carbohydrate degradation by this key member of the rumen ecosystem. Expand
Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation
TLDR
The results uncover a previously unrecognized enzymatic activity in the gut microbiota, which may contribute to the adaptation of intestinal bacteria to the mucosal environment in health and disease. Expand
...
1
2
3
4
5
...