The Roles of Lysosomes in Inflammation and Autoimmune Diseases.

@article{Ge2015TheRO,
  title={The Roles of Lysosomes in Inflammation and Autoimmune Diseases.},
  author={Wei Ge and Dongxu Li and Yanpan Gao and Xuetao Cao},
  journal={International reviews of immunology},
  year={2015},
  volume={34 5},
  pages={415-31}
}
Lysosomes perform a range of functions, some of which, such as degradation, are common to all cell types. Others, such as secretion or lysosomal exocytosis, are more specialised and tend to involve fusion of this organelle with the cell surface to release its contents. This review describes lysosomal regulation of the inflammatory glucocorticoid signaling pathways, and summarizes the roles of lysosomes in negatively or positively modulating the production of inflammatory cytokines. We also… CONTINUE READING

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