The Role of the PAX8/PPARγ Fusion Oncogene in Thyroid Cancer

  title={The Role of the PAX8/PPARγ Fusion Oncogene in  Thyroid Cancer},
  author={Kimberly A. Placzkowski and Honey Vodur Reddi and Stefan K. G. Grebe and Norman L. Eberhardt and Bryan Mciver},
  journal={PPAR Research},
  pages={1033 - 1049}
Thyroid cancer is uncommon and exhibits relatively low mortality rates. However, a subset of patients experience inexorable growth, metastatic spread, and mortality. Unfortunately, for these patients, there have been few significant advances in treatment during the last 50 years. While substantial advances have been made in recent years about the molecular genetic events underlying papillary thyroid cancer, the more aggressive follicular thyroid cancer remains poorly understood. The recent… CONTINUE READING
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