The Role of the FOXP Family of Transcription Factors in ASD

  title={The Role of the FOXP Family of Transcription Factors in ASD},
  author={John M. Bowers and Genevieve Konopka},
  booktitle={Disease markers},
Autism spectrum disorders (ASD) is a neurodevelopmental disease with complex genetics; however, the genes that are responsible for this disease still remain mostly unknown. Here, we focus on the FOXP family of transcription factors as there is emerging evidence strongly linking these genes to ASD and other genes implicated in ASD. The FOXP family of genes includes three genes expressed in the central nervous system: FOXP1, FOPX2, and FOXP4. This unique group of transcription factors has known… CONTINUE READING
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Genetic variants of FOXP 2 and KIAA 0319 / TTRAP / THEM 2 locus are associated with altered brain activation in distinct languagerelated regions

  • P Pinel, F Fauchereau, A Moreno
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