The Role of the Biochemical and Biophysical Environment in Chondrogenic Stem Cell Differentiation Assays and Cartilage Tissue Engineering

@article{Wescoe2008TheRO,
  title={The Role of the Biochemical and Biophysical Environment in Chondrogenic Stem Cell Differentiation Assays and Cartilage Tissue Engineering},
  author={Kristin E. Wescoe and Rebecca C. Schugar and Constance R. Chu and Bridget M. Deasy},
  journal={Cell Biochemistry and Biophysics},
  year={2008},
  volume={52},
  pages={85-102}
}
The field of regenerative medicine offers hope for the development of a cell-based therapy for the repair of articular cartilage (AC). Yet, the greatest challenge in the use of stem cells for tissue repair, is understanding how the cells respond to stimuli and using that knowledge to direct cell fate. Novel methods that utilize stem cells in cartilage regeneration will require specific spatio-temporal controls of the biochemical and biophysical signaling environments. Current chondrogenic… CONTINUE READING

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