The Role of Weakly Acidic Reflux in Proton Pump Inhibitor Failure, Has Dust Settled?

Abstract

Patients that do not respond satisfactorily to standard proton pump inhibitor (PPI) treatment have become the most common presentation of gastro-esophageal reflux disease (GERD) in third referral gastrointestinal practices. The causes of refractory GERD include lack of compliance with treatment, residual acid reflux and weakly acidic reflux, esophageal… (More)
DOI: 10.5056/jnm.2010.16.3.258

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