The Role of Vitamin D in Atopic Dermatitis

@article{Dbiska2015TheRO,
  title={The Role of Vitamin D in Atopic Dermatitis},
  author={Anna Dębińska and Hanna Sikorska-Szaflik and Magdalena Urbanik and Andrzej Boznański},
  journal={Dermatitis},
  year={2015},
  volume={26},
  pages={155–161}
}
Vitamin D has been suggested to have an important impact on a much wider aspects on human health than calcium homeostasis and mineral metabolism, specifically in the field of human immunology. It has been reported that vitamin D influences the regulation of both innate and adaptive immune systems, which makes the association between vitamin D and allergic diseases a field of interest. Although many studies have sought to determine whether vitamin D has an influence on progression of allergic… Expand
Vitamin D and Microbiota: Is There a Link with Allergies?
TLDR
The influence of the microbiome and vitamin D on the immune system with a particular focus on allergic diseases is summarized and the necessity of further studies on the use of probiotics and of a correct intake of vitamin D is discussed. Expand
The relationship between severity of disease and vitamin D levels in children with atopic dermatitis
TLDR
A low serum vitamin D level is inversely associated with severity of AD in children, and there is a need for more detailed and prospective studies to determine its relation to AD severity. Expand
Vitamin D levels and susceptibility to asthma, elevated immunoglobulin E levels, and atopic dermatitis: A Mendelian randomization study
TLDR
No evidence that genetically determined reduction in 25OHD levels conferred an increased risk of asthma, atopic dermatitis, or elevated total serum IgE is found, suggesting that efforts to increase vitamin D are unlikely to reduce risks of atopic disease. Expand
The impact of vitamin D supplementation as an adjuvant therapy on clinical outcomes in patients with severe atopic dermatitis: A randomized controlled trial
TLDR
Vitamin D supplementation could be an effective adjuvant treatment that improves the clinical outcomes in severe atopic dermatitis. Expand
Extraskeletal actions of vitamin D
  • D. Bikle
  • Biology, Medicine
  • Annals of the New York Academy of Sciences
  • 2016
TLDR
The role of vitamin D signaling in a number of extraskeletal tissues is examined and the success of translating these findings into treatments of human diseases affecting those extracellular tissues is assessed. Expand
Potential Treatments for Atopic Dermatitis
TLDR
Through novel therapies such as cytokine-targeting therapy, miRNA or suppression of thymic stromal lymphopoietin, patients with AD could have better quality of life with less morbidity. Expand
Estimation of Calcidiol Level in Serum of Atopic Dermatitis Patients before and after NB-UVB Phototherapy in Comparison to Oral Vitamin D Therapy
TLDR
The current study demonstrated the high efficacy of oral supplementation of calcidiol in the management of AD children that was comparable to documented results of NB-UVB. Expand
Evaluation of 1,25-dihydroxyvitamin D3 pathway in patients with chronic urticaria
TLDR
It is demonstrated that change in Vit D pathway in the level of gene or protein may be a risk factor for progression of CU. Expand
Prenatal PM2.5 exposure/vitamin D- associated early persistent atopic dermatitis via placental methylation.
  • Song-I. Yang, Seung-Hwa Lee, +20 authors S. Hong
  • Medicine
  • Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
  • 2020
TLDR
Higher PM2.5 during the first trimester of pregnancy and low CB vitamin D affected early onset persistent AD, and the most sensitive window was weeks 6-7 of gestation, where placental DNA methylation mediated this effect. Expand
Association between genetic variation within vitamin D receptor‐DNA binding sites and risk of basal cell carcinoma
TLDR
The hypothesis that inherited common variation in VDR binding sites affects the development of BCC is supported, and two SNPs at new loci are identified for the first time as independently related to BCC risk in meta‐analysis. Expand
...
1
2
...

References

SHOWING 1-10 OF 83 REFERENCES
Update on the Role of Systemic Vitamin D in Atopic Dermatitis
TLDR
A review of the present literature suggests a potentially significant role for vitamin D in the treatment of AD, and shows that, in individuals with AD who are deficient in vitamin D, repletion of vitamin D results in decreased severity of disease. Expand
[Vitamin D in allergic disorders].
TLDR
The influence of vitamin D on the course of chosen allergic diseases, such as allergic asthma, atopic dermatitis and allergic rhinitis was presented considering the possibility of contribution of allergen-specific immunotherapy. Expand
Vitamin D effects in atopic dermatitis.
TLDR
The results from this study indicate that vitamin D supplementation may help ameliorate clinical signs of the disease and can be considered as a safe and well-tolerated form of therapy. Expand
Does vitamin D intake during infancy promote the development of atopic allergy?
TLDR
This study supports previous investigations suggesting a role of vitamin D intake during infancy in the development of atopic allergy later in childhood and prevention through modified vitamin D3 supplementation in infancy could be discussed to reduce the burden ofAtopic illnesses. Expand
Vitamin D and innate and adaptive immunity.
  • M. Hewison
  • Biology, Medicine
  • Vitamins and hormones
  • 2011
TLDR
Observations support the hypothesis that vitamin D insufficiency may lead to dysregulation of human immune responses and may therefore be an underlying cause of infectious disease and immune disorders. Expand
Vitamin D supplementation in the treatment of atopic dermatitis: a clinical trial study.
TLDR
Results mention that supplementation with oral vitamin D dramatically improved disease severity in AD patients, with significant improvement in patients with mild, moderate and severe AD. Expand
Randomized Trial of Vitamin D Supplementation for Winter-Related Atopic Dermatitis in Children
TLDR
The purpose of this study was to determine the effect of vitamin D supplementation on atopic dermatitis (AD) that worsened in the winter. Expand
Vitamin D Level in Children Is Correlated with Severity of Atopic Dermatitis but Only in Patients with Allergic Sensitizations
TLDR
Vitamin D may affect the severity of AD, especially in children with allergic sensitization, and was not correlated with total IgE and eosinophil percentage in either AD group. Expand
Vitamin D deficiency is associated with diagnosis and severity of childhood atopic dermatitis
TLDR
This case–control study investigated the impact of vitamin D deficiency on atopic dermatitis diagnosis and severity in Hong Kong Chinese children and found no clear relationship between vitamin D and AD. Expand
Cord Blood 25-Hydroxyvitamin D 3 and Allergic Disease During Infancy
  • 2012
OBJECTIVE: There has been growing interest in vitamin D insufficiency as a predisposing factor for allergy development based on immunoregulatory properties and epidemiological studies. The aim ofExpand
...
1
2
3
4
5
...