The Role of Vascular Endothelial Growth Factor in Metastatic Prostate Cancer to the Skeleton

@inproceedings{Roberts2013TheRO,
  title={The Role of Vascular Endothelial Growth Factor in Metastatic Prostate Cancer to the Skeleton},
  author={Emma Roberts and Davina A. F. Cossigny and Gerald M Y Quan},
  booktitle={Prostate cancer},
  year={2013}
}
Despite the clinical implication and high incidence of bone and spinal metastases, the molecular mechanisms behind prostate cancer metastasis to bone and spine are not well understood. In this review the molecular mechanisms that may contribute to the highly metastatic phenotype of prostate cancer are discussed. Proangiogenic factors such as vascular endothelial growth factor (VEGF) have been shown to not only aid in the metastatic capabilities of prostate cancer but also encourage the… CONTINUE READING

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