The Role of Tyrosine Phosphorylation of Protein Kinase C Delta in Infection and Inflammation

@inproceedings{Yang2019TheRO,
  title={The Role of Tyrosine Phosphorylation of Protein Kinase C Delta in Infection and Inflammation},
  author={Qingliang Yang and Jordan C. Langston and Yuan He Tang and Mohammad Framurz K. Kiani and Laurie E Kilpatrick},
  booktitle={International journal of molecular sciences},
  year={2019}
}
Protein Kinase C (PKC) is a family composed of phospholipid-dependent serine/threonine kinases that are master regulators of inflammatory signaling. The activity of different PKCs is context-sensitive and these kinases can be positive or negative regulators of signaling pathways. The delta isoform (PKCδ) is a critical regulator of the inflammatory response in cancer, diabetes, ischemic heart disease, and neurodegenerative diseases. Recent studies implicate PKCδ as an important regulator of the… CONTINUE READING

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