The Role of Sumoylation in Senescence.

Abstract

Cellular senescence is a program initiated by many stress signals including aberrant activation of oncogenes, DNA damage, oxidative lesions and telomere attrition. Once engaged senescence irreversibly limits cellular proliferation and potently prevents tumor formation in vivo. The precise mechanisms driving the onset of senescence are still not completely… (More)
DOI: 10.1007/978-3-319-50044-7_13

Topics

Cite this paper

@article{Scurr2017TheRO, title={The Role of Sumoylation in Senescence.}, author={Lyndee L. Scurr and Sebastian Haferkamp and Helen Rizos}, journal={Advances in experimental medicine and biology}, year={2017}, volume={963}, pages={215-226} }