• Medicine
  • Published 2001

The Role of Stress Proteins in Cellular Resistance to Photodynamic Therapy in Bladder Cancer T24 Cells and Colon Cancer HT29 Cells

@inproceedings{Hanlon2001TheRO,
  title={The Role of Stress Proteins in Cellular Resistance to Photodynamic Therapy in Bladder Cancer T24 Cells and Colon Cancer HT29 Cells},
  author={John J. Hanlon},
  year={2001}
}
As Photodynamic Therapy (PDT) becomes increasingly popular as a treatment modality for some solid tumours, the need for a better understanding of the mechanism(s) of action and resistance are paramount. To this end we have generated Photofrin® PDT­ induced resistant variants to numerous cell lines including the colon cancer cell line HT29. There is significant evidence indicating that stress proteins play an important role in determining the outcome of PDT on a cell. In this thesis the roles of… CONTINUE READING

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