The Role of Sleep in Learning and Memory

@article{Maquet2001TheRO,
  title={The Role of Sleep in Learning and Memory},
  author={Pierre Maquet},
  journal={Science},
  year={2001},
  volume={294},
  pages={1048 - 1052}
}
  • P. Maquet
  • Published 2 November 2001
  • Biology, Psychology
  • Science
Sleep has been implicated in the plastic cerebral changes that underlie learning and memory. Indications that sleep participates in the consolidation of fresh memory traces come from a wide range of experimental observations. At the network level, reactivations during sleep of neuronal assemblies recently challenged by new environmental circumstances have been reported in different experimental designs. These neuronal assemblies are proposed to be involved in the processing of memory traces… 
View on AAAS
ncbi.nlm.nih.gov
659 Citations
Highly Influential Citations
20
Background Citations
247
Methods Citations
12
Results Citations
13

659 Citations

Citation Type

Citation Type

The molecular neurobiology of the sleep-deprived, fuzzy brain
TLDR
This issue of Science Signaling, Tudor et al. identify one molecular component underlying the effects of sleep on memory function: dynamic experience-dependent regulation of protein synthesis in the hippocampus.
Contribution of sleep to memory consolidation
TLDR
The available data indicate a positive influence of sleep on memory consolidation, and the selective effects of sleep components, such as slow waves or spindles, are being characterized.
Reciprocal interaction of sleep and synaptic plasticity.
TLDR
An overview of converging perspectives across a variety of brain regions and species proposes the developing visual pathway as a fruitful model for comprehensive understanding of sleep and synaptic plasticity.
Memory processing during sleep mechanisms and evidence from neuroimaging studies
TLDR
This review provides a summary description of the main behavioural, neurophysiological and hemodynamic features of sleep, with a special emphasis on sleep mechanisms deemed potentially important to support sleep-related brain plasticity and memory consolidation.
Sleep-dependent consolidation in multiple memory systems
TLDR
It is found that brain activity during sleep contains information about the kind of visual stimuli that were learned earlier, which indicates that sleep not only strengthens memory, but also reorganizes the contributing neural circuits.
Slow-wave sleep, acetylcholine, and memory consolidation
  • A. E. Power
  • Biology, Psychology
    Proceedings of the National Academy of Sciences of the United States of America
  • 2004
TLDR
New findings by Gais and Born presented in this issue of PNAS provide compelling evidence in human subjects that SWS and the accompanying low levels of acetylcholine during SWS may mediate a critical memory consolidation process.
Molecular Mechanisms of Memory Consolidation That Operate During Sleep
TLDR
The current knowledge of molecular mechanisms of memory consolidation during sleep impact synaptic function and engram formation is summarized and the several unknowns that hinder a deeper appreciation of such mechanisms are discussed.
Sleep and memory consolidation: The role of electrophysiological neuroimaging
SummaryMemory consolidation involves a complex series of molecular, cellular and network-level processes that take place on time scales from millisecond to months. Evidence from a wide range of…
Sleep transforms the cerebral trace of declarative memories
TLDR
Using functional MRI, it is shown that postlearning sleep enhances hippocampal responses during recall of word pairs 48 h after learning, indicating intrahippocampal memory processing during sleep, and that sleep induces a memory-related functional connectivity between the hippocampus and the mPFC.
Evidence for sleep-dependent memory consolidation in humans and mice
  • D. Cai
  • Biology, Psychology
  • 2010
TLDR
A naturalistic method to examine whether Pavlovian fear conditioning is enhanced after a sleep phase, as compared with an equivalent passage of an awake phase found that sleep selectively enhanced hippocampus-dependent memory in mice, and REM sleep, compared to NREM sleep and quiet wake, improved problem solving by assimilating new information with past experience to create a richer network for future use.
...
1
2
3
4
5
...

References

Brainstem Control of Wakefulness and Sleep
A monograph communicating the current realities and future possibilities of unifying basic studies on anatomy and cellular physiology with investigations of the behavioral and physiological events of…