The Role of Serotonin in Eating Disorders

@article{Leibowitz2012TheRO,
  title={The Role of Serotonin in Eating Disorders},
  author={Sarah F. Leibowitz},
  journal={Drugs},
  year={2012},
  volume={39},
  pages={33-48}
}
SummaryRecent pharmacological studies have more precisely characterised the nature of the inhibitory effect of brain serotonin (5-hydroxytryptamine) on feeding behaviour. Thus, the brain sites and receptors involved have been identified, and a possible physiological role of endogenous serotonin in controlling natural patterns of eating and nutrient selection has been defined. The medial hypothalamus is believed to be a critical location in the mediation of serotonin’s action. Specifically, the… 
Neurochemical Mode of Action of Drugs which Modify Feeding through The 5-HT System
Publisher Summary Increasing evidence from animal studies indicates serotonin (5-hydroxytryptamine, 5-HT) as a key mediator in the control of food intake. Serotonin reduces food intake, especially of
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Brain serotonin (5-HT) is known to have an inhibitory effect on feeding behavior, and pharmacological and biochemical evidence in humans suggests that disturbances in brain 5-HT may mediate certain symptoms of eating disorders.
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