The Role of Scavenger Receptor B1 in Infection with Mycobacterium tuberculosis in a Murine Model

@inproceedings{Schfer2009TheRO,
  title={The Role of Scavenger Receptor B1 in Infection with Mycobacterium tuberculosis in a Murine Model},
  author={Georgia Sch{\"a}fer and Reto Guler and Graeme I. Murray and Frank Brombacher and Gordon D Brown},
  booktitle={PloS one},
  year={2009}
}
BACKGROUND The interaction between Mycobacterium tuberculosis (Mtb) and host cells is complex and far from being understood. The role of the different receptor(s) implicated in the recognition of Mtb in particular remains poorly defined, and those that have been found to have activity in vitro were subsequently shown to be redundant in vivo. METHODS AND FINDINGS To identify novel receptors involved in the recognition of Mtb, we screened a macrophage cDNA library and identified scavenger… CONTINUE READING