The Role of Protein Arginine Methyltransferases in Inflammatory Responses

@inproceedings{Kim2016TheRO,
  title={The Role of Protein Arginine Methyltransferases in Inflammatory Responses},
  author={Ji Hye Kim and Byong Chul Yoo and Woo Seok Yang and Eunji Kim and Sungyoul Hong and Jae Youl Cho},
  booktitle={Mediators of inflammation},
  year={2016}
}
Protein arginine methyltransferases (PRMTs) mediate the methylation of a number of protein substrates of arginine residues and serve critical functions in many cellular responses, including cancer development, progression, and aggressiveness, T-lymphocyte activation, and hepatic gluconeogenesis. There are nine members of the PRMT family, which are divided into 4 types (types I-IV). Although most PRMTs do not require posttranslational modification (PTM) to be activated, fine-tuning modifications… CONTINUE READING

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