The Role of Protein Arginine Methyltransferases in Inflammatory Responses

@article{Kim2016TheRO,
  title={The Role of Protein Arginine Methyltransferases in Inflammatory Responses},
  author={Ji Hye Kim and B. C. Yoo and W. Yang and E. Kim and Sungyoul Hong and J. Cho},
  journal={Mediators of Inflammation},
  year={2016},
  volume={2016}
}
  • Ji Hye Kim, B. C. Yoo, +3 authors J. Cho
  • Published 2016
  • Biology, Medicine
  • Mediators of Inflammation
  • Protein arginine methyltransferases (PRMTs) mediate the methylation of a number of protein substrates of arginine residues and serve critical functions in many cellular responses, including cancer development, progression, and aggressiveness, T-lymphocyte activation, and hepatic gluconeogenesis. There are nine members of the PRMT family, which are divided into 4 types (types I–IV). Although most PRMTs do not require posttranslational modification (PTM) to be activated, fine-tuning modifications… CONTINUE READING
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