The Role of Peroxisome Proliferator-Activated Receptors in Pulmonary Vascular Disease

@article{Nisbet2007TheRO,
  title={The Role of Peroxisome Proliferator-Activated Receptors in
Pulmonary Vascular Disease},
  author={Rachel E. Nisbet and Roy Lee Sutliff and Craig M Hart},
  journal={PPAR Research},
  year={2007},
  volume={2007},
  pages={645 - 650}
}
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the nuclear hormone receptor superfamily that regulate diverse physiological processes ranging from lipogenesis to inflammation. Recent evidence has established potential roles of PPARs in both systemic and pulmonary vascular disease and function. Existing treatment strategies for pulmonary hypertension, the most common manifestation of pulmonary vascular disease, are limited by an… CONTINUE READING