The Role of Oxytocin in Human Affect

@article{Kemp2011TheRO,
  title={The Role of Oxytocin in Human Affect},
  author={A. Kemp and A. Guastella},
  journal={Current Directions in Psychological Science},
  year={2011},
  volume={20},
  pages={222 - 231}
}
Social behavior is crucial for day-to-day activities, and oxytocin has emerged as playing a central regulatory role. Oxytocin increases positive social emotions such as trust and altruism, leading to the hypothesis that oxytocin facilitates positive prosocial behaviors. However, other findings suggest that oxytocin may play a more general role that includes the facilitation of negative social emotions. These findings have led to the broader social-salience hypothesis. We propose a third… Expand

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References

SHOWING 1-10 OF 41 REFERENCES
Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress
TLDR
Oxytocin seems to enhance the buffering effect of social support on stress responsiveness, concur with data from animal research suggesting an important role of oxytocin as an underlying biological mechanism for stress-protective effects of positive social interactions. Expand
Oxytocin Modulates Neural Circuitry for Social Cognition and Fear in Humans
TLDR
It is shown that human amygdala function is strongly modulated by oxytocin, and this results indicate a neural mechanism for the effects of Oxytocin in social cognition in the human brain and provide a methodology and rationale for exploring therapeutic strategies in disorders in which abnormal amygdala function has been implicated, such as social phobia or autism. Expand
Oxytocin increases trust in humans
TLDR
It is shown that intranasal administration of oxytocin, a neuropeptide that plays a key role in social attachment and affiliation in non-human mammals, causes a substantial increase in trust among humans, thereby greatly increasing the benefits from social interactions. Expand
Promoting social behavior with oxytocin in high-functioning autism spectrum disorders
TLDR
It is found that after oxytocin inhalation, patients exhibited stronger interactions with the most socially cooperative partner and reported enhanced feelings of trust and preference, suggesting a therapeutic potential of Oxytocin through its action on a core dimension of autism. Expand
Intranasal Oxytocin Increases Positive Communication and Reduces Cortisol Levels During Couple Conflict
TLDR
These results are in line with animal studies indicating that central oxytocin facilitates approach and pair bonding behavior, and imply an involvement of oxytocIn in couple interaction and close relationships in humans. Expand
Oxytocin Attenuates Amygdala Responses to Emotional Faces Regardless of Valence
TLDR
A modulatory role of oxytocin on amygdala responses to facial expressions irrespective of their valence is suggested, which might reflect reduced uncertainty about the predictive value of a social stimulus and thereby facilitates social approach behavior. Expand
Does oxytocin influence the early detection of angry and happy faces?
TLDR
The results of this study suggest that oxytocin may not influence the detection of positive and threatening social stimuli at early perceptual levels of processing, and may have greater influence in altering the cognitive processing of social valence at more conceptual and elaborate levels ofprocessing. Expand
Oxytocin Enhances Amygdala-Dependent, Socially Reinforced Learning and Emotional Empathy in Humans
TLDR
Findings provide the first demonstration that OT can facilitate amygdala-dependent, socially reinforced learning and emotional empathy in men, as well as two patients with selective bilateral damage to the amygdala. Expand
Oxytocin Improves “Mind-Reading” in Humans
TLDR
Oxytocin improves the ability to infer the mental state of others from social cues of the eye region, and might play a role in the pathogenesis of autism spectrum disorder, which is characterized by severe social impairment. Expand
Oxytocin Attenuates Affective Evaluations of Conditioned Faces and Amygdala Activity
TLDR
The data suggest that oxytocin modulates the expression of evaluative conditioning for socially relevant faces via influences on amygdala and fusiform gyrus, an effect that may explain its prosocial effects. Expand
...
1
2
3
4
5
...