The Role of Opioid Receptor on the Analgesic Action of Intrathecal Sildenafil in Rats

@inproceedings{Lee2007TheRO,
  title={The Role of Opioid Receptor on the Analgesic Action of Intrathecal Sildenafil in Rats},
  author={Hyung Gon Lee and Chang Young Jeong and Myung Ha Yoon and Woong Mo Kim and Seung Heon Shin and Yeo Ok Kim and Lan Ji Huang and Jin Hua Cui},
  year={2007}
}
transmission. The aim of this study was to examine the role of opioid receptor in the effect of sildenafil on the nociception evoked by formalin injection. Methods: Rats were implanted with lumbar intrathecal catheters. Formalin testing was used as a nociceptive model. Formalin-induced nociceptive behavior (flinching response) was observed. To clarify the role of the opioid receptor for the analgesic action of sildenafil, naloxone was administered intrathecally 10 min before sildenafil delivery… CONTINUE READING

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