The Role of Nitric Oxide in Dilating the Fetal Ductus Arteriosus in Rats

Abstract

Prostaglandin E is a major dilator of the fetal ductus arteriosus (DA), but the role of nitric in fetal ductal dilation has not been established. We studied the effects of a potent nitric oxide synthase inhibitor. Nω-nitro-L-arginine methyl ester (L-NAME), on the fetal DA in rats. L-NAME was injected into the dorsum of pregnant rats, and fetal DA was… (More)
DOI: 10.1203/00006450-199909000-00010

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