The Role of Neurogenic Inflammation in Blood-Brain Barrier Disruption and Development of Cerebral Oedema Following Acute Central Nervous System (CNS) Injury

@inproceedings{SorbyAdams2017TheRO,
  title={The Role of Neurogenic Inflammation in Blood-Brain Barrier Disruption and Development of Cerebral Oedema Following Acute Central Nervous System (CNS) Injury},
  author={Annabel J. Sorby-Adams and Amanda M. Marcoionni and Eden R. Dempsey and Joshua A. Woenig and Renée Jade Turner},
  booktitle={International journal of molecular sciences},
  year={2017}
}
Acute central nervous system (CNS) injury, encompassing traumatic brain injury (TBI) and stroke, accounts for a significant burden of morbidity and mortality worldwide, largely attributable to the development of cerebral oedema and elevated intracranial pressure (ICP). Despite this, clinical treatments are limited and new therapies are urgently required to improve patient outcomes and survival. Originally characterised in peripheral tissues, such as the skin and lungs as a neurally-elicited… CONTINUE READING
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