The Role of NK Cells in Autoimmune Disease

@article{Baxter2002TheRO,
  title={The Role of NK Cells in Autoimmune Disease},
  author={A. Baxter and M. Smyth},
  journal={Autoimmunity},
  year={2002},
  volume={35},
  pages={1 - 14}
}
  • A. Baxter, M. Smyth
  • Published 2002
  • Medicine
  • Autoimmunity
  • NK cells are a subset of mononuclear cells which have long been suspected of playing an immuno-regulatory role in the prevention of autoimmune diseases. Here, we briefly discuss the characteristics of NK cells--particularly what is known of their functional capabilities--and summarise the major findings from studies of NK cells in human and animals susceptible to three major autoimmune diseases: multiple sclerosis, systemic lupus erythematosus and type 1 (autoimmune) diabetes mellitus. In each… CONTINUE READING
    NK cells in autoimmune disease.
    28
    The role of natural killer cells in pathogenesis of autoimmune diseases
    37
    NK Cells and Type 1 Diabetes
    43
    The Role of NK Cells and NK Cell Receptors inAutoimmune Disease
    27
    Natural killer cells and autoimmunity
    126
    The Role of NK Cells in the Autoimmune Thyroid Disease-associated Pregnancy Loss
    21
    NK cells in autoimmunity: a two-edg'd weapon of the immune system.
    95

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 217 REFERENCES
    Dysfunction of natural killer cells in multiple sclerosis: a possible pathogenetic factor.
    88
    Regulation of Experimental Autoimmune Encephalomyelitis by Natural Killer (NK) Cells
    221
    Regulation of adaptive immunity by natural killer cells
    76
    Role of natural killer cells and TCRγ δ T cells in acute autoimmune encephalomyelitis
    153
    Cytometric and functional analyses of NK and NKT cell deficiencies in NOD mice.
    170
    Natural killing in systemic lupus erythematosus: inhibitory effects of serum.
    13
    Development and tolerance of natural killer cells.
    104