The Role of Molecular Pathology in the Diagnosis of Cutaneous Lymphomas

  title={The Role of Molecular Pathology in the Diagnosis of Cutaneous Lymphomas},
  author={Philipp W Raess and Adam Bagg},
  booktitle={Pathology research international},
Primary cutaneous lymphomas can be difficult to be distinguished from reactive mimics, even when integrating histologic, immunophenotypic, and clinical findings. Molecular studies, especially PCR-based antigen receptor gene rearrangement (ARGR) analysis, are frequently useful ancillary studies in the evaluation of cutaneous lymphoproliferations. The biologic basis of ARGR studies is discussed, as well as a comparison of various current protocols. The pitfalls and limitations of ARGR analysis… CONTINUE READING
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