The Role of Methionine Oxidation/Reduction in the Regulation of Immune Response.

Abdulbaki Agbas, Jackob Moskovitz
Published 2009 in Current signal transduction therapy

Abstract

Methionine oxidation by reactive oxygen species and reduction mediated by the methionine sulfoxide reductase (Msr) system may attenuate protein function in signal transduction pathways. This review will focus on two potential protein targets for methionine oxidation involved in signal transduction of the immune response: Ca(2+)/calmodulin-regulated… (More)

DOI: 10.2174/157436209787048748

Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice

Cheril Tapia-Rojas, Carolina B. Lindsay, +5 authors Nibaldo C. Inestrosa
Molecular Neurodegeneration
2015

The Role of Methionine Oxidation/Reduction in the Regulation of Immune Response.

Abstract

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Cited By

Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice

Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin.

Oxidation-Induced Conformational Changes in Calcineurin Determined by Covalent Labeling and Tandem Mass Spectrometry

A molecular dynamics and quantum mechanics/molecular mechanics study of the catalytic reductase mechanism of methionine sulfoxide reductase A: formation and reduction of a sulfenic acid.

Structural and functional impact of site-directed methionine oxidation in myosin.

Protein oxidation: role in signalling and detection by mass spectrometry

Regulation of Redox Signaling by Selenoproteins

References

Identification of a peptide fragment of DSCR1 that competitively inhibits calcineurin activity in vitro and in vivo.

Prolonged selenium-deficient diet in MsrA knockout mice causes enhanced oxidative modification to proteins and affects the levels of antioxidant enzymes in a tissue-specific manner.

Phosphorylation inhibits turnover of the tau protein by the proteasome: influence of RCAN1 and oxidative stress.

Evidence that calcineurin is required for the genesis of bone-resorbing osteoclasts.

Activated calcineurin ameliorates contraction-induced injury to skeletal muscles of mdx dystrophic mice.

IkappaB is a sensitive target for oxidation by cell-permeable chloramines: inhibition of NF-kappaB activity by glycine chloramine through methionine oxidation.

Signaling pathways in skeletal muscle remodeling.

Decreased activity and increased aggregation of brain calcineurin during aging.

Distinct roles of calcineurin-nuclear factor of activated T-cells and protein kinase A-cAMP response element-binding protein signaling in presynaptic differentiation.

Methionine oxidation, alpha-synuclein and Parkinson's disease.

Slides referencing similar topics

The Role of Methionine Oxidation/Reduction in the Regulation of Immune Response.

Abstract

Topics

Figures and Tables

Cited By

Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice

Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin.

Oxidation-Induced Conformational Changes in Calcineurin Determined by Covalent Labeling and Tandem Mass Spectrometry

A molecular dynamics and quantum mechanics/molecular mechanics study of the catalytic reductase mechanism of methionine sulfoxide reductase A: formation and reduction of a sulfenic acid.

Structural and functional impact of site-directed methionine oxidation in myosin.

Protein oxidation: role in signalling and detection by mass spectrometry

Regulation of Redox Signaling by Selenoproteins

References

Identification of a peptide fragment of DSCR1 that competitively inhibits calcineurin activity in vitro and in vivo.

Prolonged selenium-deficient diet in MsrA knockout mice causes enhanced oxidative modification to proteins and affects the levels of antioxidant enzymes in a tissue-specific manner.

Phosphorylation inhibits turnover of the tau protein by the proteasome: influence of RCAN1 and oxidative stress.

Evidence that calcineurin is required for the genesis of bone-resorbing osteoclasts.

Activated calcineurin ameliorates contraction-induced injury to skeletal muscles of mdx dystrophic mice.

IkappaB is a sensitive target for oxidation by cell-permeable chloramines: inhibition of NF-kappaB activity by glycine chloramine through methionine oxidation.

Signaling pathways in skeletal muscle remodeling.

Decreased activity and increased aggregation of brain calcineurin during aging.

Distinct roles of calcineurin-nuclear factor of activated T-cells and protein kinase A-cAMP response element-binding protein signaling in presynaptic differentiation.

Methionine oxidation, alpha-synuclein and Parkinson's disease.

Similar Papers

Slides referencing similar topics