The Role of Mast Cells in Tuberculosis: Orchestrating Innate Immune Crosstalk?

@inproceedings{GarciaRodriguez2017TheRO,
  title={The Role of Mast Cells in Tuberculosis: Orchestrating Innate Immune Crosstalk?},
  author={Karen M. Garcia-Rodriguez and Anu Goenka and M. Teresa Alonso-Rasgado and Rogelio Hern{\'a}ndez-Pando and Silvia Bulfone-Paus},
  booktitle={Front. Immunol.},
  year={2017}
}
Tuberculosis causes more annual deaths globally than any other infectious disease. However, progress in developing novel vaccines, diagnostics, and therapies has been hampered by an incomplete understanding of the immune response to Mycobacterium tuberculosis (Mtb). While the role of many immune cells has been extensively explored, mast cells (MCs) have been relatively ignored. MCs are tissue resident cells involved in defense against bacterial infections playing an important role mediating… CONTINUE READING
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