The Role of Mammary Stroma in Modulating the Proliferative Response to Ovarian Hormones in the Normal Mammary Gland

@article{Woodward1998TheRO,
  title={The Role of Mammary Stroma in Modulating the Proliferative Response to Ovarian Hormones in the Normal Mammary Gland},
  author={Terry L. Woodward and Jian Wei Xie and Sandra Z. Haslam},
  journal={Journal of Mammary Gland Biology and Neoplasia},
  year={1998},
  volume={3},
  pages={117-131}
}
Postnatal mammary gland development is highlydependent on the ovarian steroids, estrogen andprogesterone. However, evidence from both in vitro andin vivo studies indicates that steroid-induceddevelopment occurs indirectly, requiring stromalcooperation in epithelial proliferation andmorphogenesis. Stromal cells appear to influenceepithelial cell behavior by secretion of growth factorsand/or by altering the composition of the extracellular matrix inwhich epithelial cells reside. This review will… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.
33 Citations
52 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 52 references

A . histochemical evaluation of human tumors

  • J. M. Bennett, S. Z. Haslam
  • Cancer Res .
  • 1998

Altered integrin

  • M. M. Zutter, H. Sun, S. A. Santoro
  • 1998

Extracellular matrix regulates ovarian hormonedependen t proliferation of mouse mammary The authors would like to thank Drs

  • K. S. Korach
  • Endocrinology
  • 1997
1 Excerpt

A role for insulin

  • H. Huynh, X. F. Yang, M. Pollak
  • 1996

Expres - protein ( mac 25 ) in senescent human mammary epithelial cells sion of basic fibroblast growth factor and its mRNA in uterine and induced expression with retinoic acid

  • X. F. Yang, M. Pollak
  • Proc . Natl . Acad . endometrium during the…
  • 1996

Similar Papers

Loading similar papers…