The Role of Keratinocyte-derived Chemokine in Hemorrhage-induced Acute Lung Injury in Mice

  title={The Role of Keratinocyte-derived Chemokine in Hemorrhage-induced Acute Lung Injury in Mice},
  author={Byoung Hoon Lee and Tae Jin Lee and Jae Woo Jung and Dong Jin Oh and Jae Chol Choi and Jong Wook Shin and In won Park and B. W. Choi and Jae Yeol Kim},
  booktitle={Journal of Korean medical science},
Dominant inflammatory cytokines might be different depending on the underlying causes of acute lung injury (ALI). The role of kertinocyte-derived chemokine (KC), a potent chemoattractant for neutrophils, has not been clearly established in hemorrhage-induced ALI. In this study, lung injury and cytokine expression were evaluated in LPS- or hemorrhage-induced ALI models of BALB/c mice. The myeloperoxidase activities at 4 hr after hemorrhage and LPS-injection were 47.4+/-13.0 and 56.5+/-16.4 U/g… CONTINUE READING


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