The Role of Intestinal Microflora in Anti-Inflammatory Effect of Baicalin in Mice

@inproceedings{Jung2012TheRO,
  title={The Role of Intestinal Microflora in Anti-Inflammatory Effect of Baicalin in Mice},
  author={Myung-Ah Jung and Se-Eun Jang and Sung-Woon Hong and Myung Joo Hana and Dong-Hyun Kim},
  booktitle={Biomolecules & therapeutics},
  year={2012}
}
Baicalin, a main constituent of the rhizome of Scutellaria baicalensis, is metabolized to baicalein and oroxylin A in the intestine before its absorption. To understand the role of intestinal microflora in the pharmacological activities of baicalin, we investigated its anti-inflammatory effect in mice treated with and without antibiotics. Orally administered baicalin showed the anti-inflammatory effect in mice than intraperitoneally treated one, apart from intraperitoneally administered its… CONTINUE READING

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Chemical & pharmaceutical bulletin • 1990
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