The Role of Interleukin 13 in Classical Hodgkin Lymphoma

@article{Skinnider2002TheRO,
  title={The Role of Interleukin 13 in Classical Hodgkin Lymphoma},
  author={Brian F. Skinnider and Ursula Kapp and Tak Wah Mak},
  journal={Leukemia \& Lymphoma},
  year={2002},
  volume={43},
  pages={1203 - 1210}
}
The Reed-Sternberg (RS) cells of classical Hodgkin lymphoma (cHL) produce several cytokines, which are thought to account for the unique clinical and pathologic features of this disease. We previously identified interleukin (IL)-13 expression as a common feature of cHL and have studied the potential role of this cytokine as an autocrine growth factor for RS cells. IL-13 and the IL-13-specific receptor chain (IL-13R α 1) are frequently expressed in cHL-derived cell lines and in RS cells from… 
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