• Corpus ID: 92994818

The Role of Inflammation and Immune Activation in Non-AIDS related CoMorbidities in HIV infection : Determinants and Outcomes

  title={The Role of Inflammation and Immune Activation in Non-AIDS related CoMorbidities in HIV infection : Determinants and Outcomes},
  author={Chidozie Elochukwu Agu and Ikenna Kingsley Uchendu and Chigozie N Okwuosa and Peter Uwadiegwu Achukwu},
Individuals living with HIV infection on antiretroviral therapy are at an increased risk of developing non-AIDS related diseases and experience incomplete immune restoration. The path physiology has been linked to HIV-specific mechanisms as well as non-specific generalized responses to infection which are thought to contribute to the ongoing activation of the immune system. Factors such as the early loss of gastrointestinal (GI) tract mucosal integrity, the proinflammatory cytokine milieu, co… 

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