The Role of Hyaluronan and CD44 in the Pathogenesis of Lupus Nephritis

@inproceedings{Yung2012TheRO,
  title={The Role of Hyaluronan and CD44 in the Pathogenesis of Lupus Nephritis},
  author={Susan Yung and Tak Mao Chan},
  booktitle={Autoimmune diseases},
  year={2012}
}
Systemic lupus erythematosus (SLE) is a prototype autoimmune disease that affects multiorgan systems. Lupus nephritis is one of the most severe manifestations of SLE whereby immune-mediated inflammation can lead to permanent damage within the glomerular, tubulo-interstitial, and vascular compartments of the kidney, resulting in acute or chronic renal failure. The mechanisms that regulate host inflammatory responses and tissue injury are incompletely understood. Accumulating evidence suggests… CONTINUE READING
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