The Role of Health-Related Quality of Life Outcomes in Clinical Decision Making in Surgery for Esophageal Cancer: A Systematic Review

@article{Parameswaran2008TheRO,
  title={The Role of Health-Related Quality of Life Outcomes in Clinical Decision Making in Surgery for Esophageal Cancer: A Systematic Review},
  author={Rajeev Parameswaran and Angus G K McNair and Kerry N.L. Avery and Richard G. Berrisford and S. A. Wajed and Mirjam A. G. Sprangers and Jane M. Blazeby},
  journal={Annals of Surgical Oncology},
  year={2008},
  volume={15},
  pages={2372-2379}
}
BackgroundEsophagectomy for cancer offers a chance of cure but is associated with morbidity, at least a temporary reduction in health-related quality of life (HRQL), and a 5-year survival of approximately 30%. This research evaluated how and whether HRQL outcomes contribute to surgical decision making.MethodsA systematic review identified randomized trials and longitudinal and cross-sectional studies that assessed HRQL after esophagectomy with multidimensional validated questionnaires. Articles… 

Systematic review reveals limitations of studies evaluating health-related quality of life after potentially curative treatment for esophageal cancer

TLDR
Current evidence is restricted in its ability to inform practice on HRQL after potentially curative treatment for esophageal cancer and three high-quality studies were identified—two RCTs and one case-series—capable of providing robust results.

Predictors of postoperative quality of life after esophagectomy for cancer.

TLDR
Knowledge of risk factors for poor postoperative HRQL may be relevant for clinical decision making and more research is needed to see whether these factors are further predictive of poor HRQL in long-term survivors.

Systematic review: quality of life after treatment for upper gastrointestinal cancer

TLDR
This review identified few well-designed studies that also included a robust assessment of HRQL, and high-quality trials with reliable HRQL methods are required for outcomes to inform health policy and clinical decision-making.

Meta-analysis shows clinically relevant and long-lasting deterioration in health-related quality of life after esophageal cancer surgery

TLDR
Patients will experience a clinically relevant and long-lasting deterioration in HRQL after esophageal cancer surgery, however, for many HRQL outcomes, more and better quality evidence is needed.

Long-term Health-related Quality of Life Following Esophagectomy: A Nonrandomized Comparison of Thoracoscopically Assisted and Open Surgery

TLDR
This large comprehensive nonrandomized analysis of longitudinal HRQL shows that TTIL is associated with more pain and constipation than TAMK.

Quality of Life After Surgical Treatment of Early Barrett’s Cancer: A Prospective Comparison of the Ivor-Lewis Resection Versus the Modified Merendino Resection

TLDR
It is suggested that MER procedure is not superior to subtotal esophagectomy with regard to HRQL, and a significant restriction concerning global health and emotional and social functioning in this group 1 year after surgery is found.

The Influence of Surgical Factors on Persisting Symptoms 3 Years after Esophageal Cancer Surgery: A Population-Based Study in Sweden

TLDR
Surgical approach and type of anastomosis do not seem to influence the risk of general and esophageal-specific cancer symptoms 3 years after surgery for esophagal cancer.

Assessing the relationships between health-related quality of life and postoperative length of hospital stay after oesophagectomy for cancer of the oesophagus and the gastro-oesophageal junction.

  • P. NafteuxJoke Durnez P. D. De Leyn
  • Medicine
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • 2013
TLDR
The data suggest that early discharge correlates with improved postoperative HRQL outcomes and a clear decrease of the HRQL is seen at 3 months after the surgery, particularly in the LOS >10 days group.

Quality of life assessment in esophagectomy patients.

TLDR
Evaluation of health-related quality of life in esophageal cancer patients undergoing curative intent therapy, the relationship between postoperative HRQOL and survival as well the potential utility of pre-treatment HRZOL as a prognostic tool, and patient-reported pre- treatment HRQol assessment appear to predict survival better than clinician-derived performance status assessment period.

Education level and health-related quality of life after oesophageal cancer surgery: a nationwide cohort study

TLDR
Investigating whether low education level was associated with patients’ health-related quality of life (HRQOL) after oesophageal cancer resection found no such association, and low education was in general associated with worse functioning and more symptoms in certain HRQOL domains for women.
...

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