The Role of Health-Related Quality of Life Outcomes in Clinical Decision Making in Surgery for Esophageal Cancer: A Systematic Review

  title={The Role of Health-Related Quality of Life Outcomes in Clinical Decision Making in Surgery for Esophageal Cancer: A Systematic Review},
  author={R. Parameswaran and A. McNair and K. Avery and R. Berrisford and S. Wajed and M. Sprangers and J. Blazeby},
  journal={Annals of Surgical Oncology},
  • R. Parameswaran, A. McNair, +4 authors J. Blazeby
  • Published 2008
  • Medicine
  • Annals of Surgical Oncology
  • BackgroundEsophagectomy for cancer offers a chance of cure but is associated with morbidity, at least a temporary reduction in health-related quality of life (HRQL), and a 5-year survival of approximately 30%. This research evaluated how and whether HRQL outcomes contribute to surgical decision making.MethodsA systematic review identified randomized trials and longitudinal and cross-sectional studies that assessed HRQL after esophagectomy with multidimensional validated questionnaires. Articles… CONTINUE READING
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