The Role of HER2/neu Overexpression/Amplification in the Progression of Ductal Carcinoma In Situ to Invasive Carcinoma of the Breast

@article{Latta2002TheRO,
  title={The Role of HER2/neu Overexpression/Amplification in the Progression of Ductal Carcinoma In Situ to Invasive Carcinoma of the Breast},
  author={E K Latta and S Tjan and Robert K Parkes and Frances P. O'Malley},
  journal={Modern Pathology},
  year={2002},
  volume={15},
  pages={1318-1325}
}
HER2/neu overexpression/amplification is seen more frequently in ductal carcinoma in situ, particularly high-grade ductal carcinoma in situ (50–60%), than in invasive ductal carcinoma of the breast (25–30%). To date, however, the role of HER2/neu in the progression of in situ to invasive disease has not been clarified. Two hundred fifty-one breast tumors were retrieved from the pathology files at Mount Sinai Hospital. These included 91 cases of ductal carcinoma in situ, 136 cases of invasive… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 91 CITATIONS, ESTIMATED 76% COVERAGE

Sclerosing adenosis as a predictor of breast cancer bilaterality and multicentricity

  • Virchows Archiv
  • 2015
VIEW 7 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2003
2019

CITATION STATISTICS

  • 3 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 34 REFERENCES

When is a tumor marker ready for prime time? A case study of c-erbB-2 as a predictive factor in breast cancer.

  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 2001
VIEW 1 EXCERPT

Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast.

  • Clinical cancer research : an official journal of the American Association for Cancer Research
  • 1999
VIEW 1 EXCERPT

Prognostic and predictive factors in breast cancer by immunohistochemical analysis.

  • Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • 1998
VIEW 1 EXCERPT