The Role of GABA Receptor Agonists in Anesthesia and Sedation

@article{Brohan2017TheRO,
  title={The Role of GABA Receptor Agonists in Anesthesia and Sedation},
  author={Janette Brohan and Basavana Goudra},
  journal={CNS Drugs},
  year={2017},
  volume={31},
  pages={845-856}
}
GABA (γ-aminobutyric acid) receptors, of which there are two types, are involved in inhibitory synapses within the central nervous system. The GABAA receptor (GABAAR) has a central role in modern anesthesia and sedation practice, which is evident from the high proportion of agents that target the GABAAR. Many GABAAR agonists are used in anesthesia practice and sedation, including propofol, etomidate, methohexital, thiopental, isoflurane, sevoflurane, and desflurane. There are advantages and… Expand
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