The Role of Extracellular Vesicle and Tunneling Nanotube-Mediated Intercellular Cross-Talk Between Mesenchymal Stem Cells and Human Peripheral T Cells.

@article{Matula2016TheRO,
  title={The Role of Extracellular Vesicle and Tunneling Nanotube-Mediated Intercellular Cross-Talk Between Mesenchymal Stem Cells and Human Peripheral T Cells.},
  author={Zsolt Matula and Andrea M. Nemeth and P{\'e}ter Lőrincz and {\'A}ron Szepesi and Anna Br{\'o}zik and Edit Ir{\'e}n Buz{\'a}s and P{\'e}ter Lőw and Katalin N{\'e}met and Ferenc Uher and Veronika S. Urb{\'a}n},
  journal={Stem cells and development},
  year={2016},
  volume={25 23},
  pages={
          1818-1832
        }
}
The role of extracellular vesicles (EVs) in mediating the immunosuppressory properties of mesenchymal stem cells (MSCs) has recently attracted remarkable scientific interest. The aim of this work was to analyze the transport mechanisms of membrane and cytoplasmic components between T lymphocytes and adipose tissue-derived MSCs (AD-MSCs), by focusing on the role of distinct populations of EVs, direct cell-cell contacts, and the soluble mediators per se in modulating T lymphocyte function. We… CONTINUE READING
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